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Are Supplements Safe To Take With Medications?

Taking multiple drugs and supplements can increase your risk of side effects and adverse interactions, including delirium and cognitive impairment. Even herbal supplements from natural sources can have potent active ingredients and dangerous interactions with drugs, other supplements, and certain beverages and foods.

Several online resources like consumerlab.com allow you to check interactions between drugs and supplements you are taking. Most analyze drug-drug interactions. Information on drug-food, drug-supplement, or supplement-supplement interactions is also available on several sites, webmd.com, rxlist.com, drugs.com, medscape.com, though it is less thorough.

These online resources can be helpful in avoiding the most common interaction issues but may miss problems with less common supplements or herbs. To be safe, ask your physician or pharmacist about possible side effects and interactions. Have a list ready with all medications and supplements you are taking along with dosages.

Supplement Interactions With Antibiotics

Antibiotics can be affected by the supplements you take, and they can affect your ability to absorb certain vitamins and minerals.

The interaction depends on the type of antibiotic you are taking. You can search for the specific antibiotic you are taking by clicking Drug Interactions.


Some of the most common antibiotics are listed below, followed by the supplements with which they can interact. For more details use the links:

Cephalosporins (cefdinir (Omnicef), cephalexin (Cefanex, Keflex, Keftab, Biocef) etc.): Vitamin K

Amoxicillin (Trimox, Amoxil, Wymox): Bromelain, vitamin K

Tetracyclines (doxycycline (Doryx, Doxy-Caps, Bio-Tab), tetracycline hydrochloride (Achromycin V, Panmycin etc.): Calciummagnesiumiron and zinc, Dong Quai, St. John’s Wort, citrate (i.e. potassium citrate)

Fluoroquinolones (levofloxacin (Levaquin), ciprofloxacin (Cipro)): magnesium, Calcium, iron and zinc, fennel, Dong Quai, St. John’s Wort

Trimethoprim/sulfamethoxazole (Bactrim, Cotrim, Sulfatrim, Septra): Folate, PABA (para-aminobenzoic acid), potassium, white willow, St. John’s wort

Interestingly, some of the supplements noted above (folate and vitamin K) may, at times, be helpful when taking certain antibiotics like probiotics.


SOURCES: alzdiscovery, consumerlab




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